
HaLCon: Chromatography Without Complexity
Accurate, actionable protein titer in minutes, not days

Built for Bioprocess Workflows
- Make faster decisions with protein titer results in just5 minutes
- Trust your data with HPLC-level accuracy (R² > 0.99)
- Scale your throughput with seamless auto sampler compatibility
- Reduce training time —HaLCon is fully automated and easy to operate
- Compact footprint built for development and GMP labs
Real-Time Protein Titer for BioreactorSampling, IgG Quantitation, and mAb Production
For bioreactor sampling and process control, IgG quantitation, and monoclonal antibody production, HaLCon provides immediate, actionable data—keeping workflows on track and reducing costly hold times in continuous manufacturing.
At Lonza, HaLCon replaced slow HPLC measurements with rapid, accurate titer data.By spotting issues earlier and making faster decisions, their teams streamlined development workflows and reduced costly delays.
Real-Time Protein Titer for BioreactorSampling, IgG Quantitation, and mAb Production
For bioreactor sampling and process control, IgG quantitation, and monoclonal antibody production, HaLCon provides immediate, actionable data—keeping workflows on track and reducing costly hold times in continuous manufacturing.
At Lonza, HaLCon replaced slow HPLC measurements with rapid, accurate titer data.By spotting issues earlier and making faster decisions, their teams streamlined development workflows and reduced costly delays.
Features and Benefits of HaLCon
- Protein titer correlates with off-line HPLC measurements
- Sample-to-answer in less than six minutes
- Streamlined operation for ease-of-use
- No chromatography expertise required
- Sample flow path is completely contained
- Individual sample or autosampler
- Flexible manual or automated sampling information
- Compact design for a small footprint
- Minimal connections
- Protein titer correlates with off-line HPLC measurements
- Sample-to-answer in less than six minutes
- Streamlined operation for ease-of-use
- No chromatography expertise required
- Sample flow path is completely contained
- Individual sample or autosampler
- Flexible manual or automated sampling information
- Compact design for a small footprint
- Minimal connections
Accessories

Nest Autosampler
The HaLCon Analyzer can be integrated with the Nest Autosampler, to increase throughput and boost efficiency.
Features
- Multi-sample automation with fast turnaround time
- Holds up to 2 x 96 well plates or 2 x 48 (2ml vial) racks
- Low sample volume (100μL)
- Perfect titer solution for Ambr 15/250
- Cooling and non-cooling options
- High throughput titer automation saves valuable time and money
- Delivers fast and accurate results without the need for method development or specialized training
Specifications
Dimensions: 300mm x 510 mm x 360 mm (without cooling) 300 mm x 575 mm x 360 mm (with cooling)
Weight: 19 kg (without cooling) 21 kg (with cooling)
Sample Capacity: 192 (96 well plates) 96 (2 ml vials)
Injection Volume: 100 μL
Analysis Time: <6 minutes
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