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RedShiftBio at PS 37

July 13, 2023

Events

RedShiftBio at PS37

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Structural Characterization and Temperature and Pressure Stress Comparison on Ovalbumin using MMS

June 6, 2023

Videos

Structural Characterization and Temperature and Pressure Stress Comparison on Ovalbumin using MMS

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RedShiftBio at MOSBRI 2023

June 5, 2023

Events

RedShiftBio at MOSBRI 2023

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RedShiftBio at PEGS Boston Summit

May 15, 2023

Events

RedShiftBio at PEGS Boston Summit

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HaLCon Product Brochure

May 12, 2023

Brochures

HaLCon Product Brochure

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Microfluidic Modulation Spectroscopy: A Technology Platform for Ultra- sensitive Analysis of Proteins, from Structure to Activity

May 11, 2023

Webinars

Microfluidic Modulation Spectroscopy: A Technology Platform for Ultra- sensitive Analysis of Proteins, from Structure to Activity

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Structure, Stability, Similarity, and Stress Characterization of a Commercial mAb Therapeutic and Two Biosimilar Drugs Using Microfluidic Modulation Spectroscopy (MMS)

May 3, 2023

App Notes

Structure, Stability, Similarity, and Stress Characterization of a Commercial mAb Therapeutic and Two Biosimilar Drugs Using Microfluidic Modulation Spectroscopy (MMS)

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Challenges and Opportunities in Biotherapeutic Analytics: 3rd edition

April 27, 2023

Events

Challenges and Opportunities in Biotherapeutic Analytics: 3rd edition

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Application of Microfluidic Modulation Spectroscopy (MMS) for Characterizing the Secondary Structure of Mixed Food Protein Complexes

April 25, 2023

Webinars

Application of Microfluidic Modulation Spectroscopy (MMS) for Characterizing the Secondary Structure of Mixed Food Protein Complexes

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A Structural Characterization of a Monoclonal Antibody Therapeutic as Formulated and Under Multiple Conjugation Paradigms

April 10, 2023

Posters

A Structural Characterization of a Monoclonal Antibody Therapeutic as Formulated and Under Multiple Conjugation Paradigms

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How secondary structure relates to enzyme activity: The structural differences between α-chymotrypsin and its inactive precursor chymotrypsinogen determined with Microfluidic Modulation Spectroscopy (MMS)

March 29, 2023

App Notes

How secondary structure relates to enzyme activity: The structural differences between α-chymotrypsin and its inactive precursor chymotrypsinogen determined with Microfluidic Modulation Spectroscopy (MMS)

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α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer’s disease

March 23, 2023

Publications

α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer’s disease

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Secondary structure characterization of mixed food protein complexes using microfluidic modulation spectroscopy (MMS)

March 23, 2023

Publications

Secondary structure characterization of mixed food protein complexes using microfluidic modulation spectroscopy (MMS)

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RedShiftBio at Festival of Biologics US

March 20, 2023

Events

RedShiftBio at Festival of Biologics US

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Rapid and Accurate Determination of the Higher Order Structure of a Library of Proteins Using Microfluidic Modulation Spectroscopy

March 3, 2023

App Notes

Rapid and Accurate Determination of the Higher Order Structure of a Library of Proteins Using Microfluidic Modulation Spectroscopy

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Behind the App Note: Assessment of Protein Hydration, Surface Hydrophobicity, and Structure in One Single Automated Measurement

March 3, 2023

Videos

Behind the App Note: Assessment of Protein Hydration, Surface Hydrophobicity, and Structure in One Single Automated Measurement

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Lead Optimization using Microfluidic Modulation Spectroscopy

February 9, 2023

Videos

Lead Optimization using Microfluidic Modulation Spectroscopy

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RedShiftBio at Lorne Proteins 2023

February 5, 2023

Events

RedShiftBio at Lorne Proteins 2023

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Characterization of Three USP Reference Standards using Microfluidic Modulation Spectroscopy

February 1, 2023

App Notes

Characterization of Three USP Reference Standards using Microfluidic Modulation Spectroscopy

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Behind the App Note: MMS for Non-Destructive Structural Characterization: Case Study Using BSA

January 20, 2023

Videos

Behind the App Note: MMS as a Non-Destructive Structural CharacterizationTechnique: A Case Study Using BSA

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RedShiftBio at PepTalk 2023

January 16, 2023

Events

RedShiftBio at PepTalk 2023

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Assessment of Protein Hydration, Surface Hydrophobicity, and Structure in One Single Automated Measurement

January 4, 2023

App Notes

Assessment of Protein Hydration, Surface Hydrophobicity, and Structure in One Single Automated Measurement

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Behind the App Note: Detection of Pressure-Induced Protein Aggregation Using Microfluidic Modulation Spectroscopy (MMS)

December 6, 2022

Videos

Behind the App Note: Detection of Pressure-Induced Protein Aggregation Using Microfluidic Modulation Spectroscopy (MMS)

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PEGS Europe 2022: Measuring Change in Secondary Structure and Oligomeric State for a mAb in Stress and In-Process Testing with MMS and SEC

November 30, 2022

Videos

PEGS Europe 2022: Measuring Change in Secondary Structure and Oligomeric State for a mAb in Stress and In-Process Testing with MMS and SEC

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RedShiftBio at PEGS Europe 2022

November 14, 2022

Events

RedShiftBio at PEGS Europe 2022

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Sciex MasterClass On-Demand: Measuring Changes in Protein Structure with Microfluidic Modulation Spectroscopy

November 9, 2022

Videos

Sciex MasterClass On-Demand: Measuring Changes in Protein Structure with Microfluidic Modulation Spectroscopy

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Microfluidic Modulation Spectroscopy as a Non-Destructive Structural Characterization Technique: A Case Study Using Bovine Serum Albumin

November 1, 2022

App Notes

Microfluidic Modulation Spectroscopy as a Non-Destructive Structural Characterization Technique: A Case Study Using Bovine Serum Albumin

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Protein Therapeutics: Understanding the Biophysical Characterization Toolbox

October 26, 2022

Webinars

Protein Therapeutics: Understanding the Biophysical Characterization Toolbox

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RedShiftBio at Formulation & Delivery US 2022

October 11, 2022

Events

RedShiftBio at Formulation & Delivery US 2022

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Characterizing Amyloid-Forming Immunoglobulin G Light and Variable Chains Using Microfluidic Modulation Spectroscopy

October 3, 2022

App Notes

Characterizing Amyloid-Forming Immunoglobulin G Light and Variable Chains Using Microfluidic Modulation Spectroscopy

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Behind the App Note: Benchmarking the RedShiftBio Apollo MMS System Performance Versus the First-Generation AQS3®pro

September 12, 2022

Videos

Behind the App Note: Benchmarking the RedShiftBio Apollo MMS System Performance Versus the First-Generation AQS3®pro

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Benchmarking the RedShiftBio Apollo MMS System Performance Versus the First-Generation AQS3®pro

September 12, 2022

App Notes

Benchmarking the RedShiftBio Apollo MMS System Performance Versus the First-Generation AQS3®pro

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Characterizing Amyloid-Forming IgG Light and Variable Chains Using Microfluidic Modulation Spectroscopy

August 24, 2022

Videos

Characterizing Amyloid-Forming IgG Light and Variable Chains Using Microfluidic Modulation Spectroscopy

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Characterizing Amyloid-Forming Immunoglobulin G Light and Variable Chains Using Microfluidic Modulation Spectroscopy

August 23, 2022

Webinars

Characterizing Amyloid-Forming Immunoglobulin G Light and Variable Chains Using Microfluidic Modulation Spectroscopy

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Behind the App Note: Protein Dilution and Subsequent Concentration Provide a Well-Matched Sample/Buffer Pair for High-Resolution MMS

August 18, 2022

Videos

Behind the App Note: Protein Dilution and Subsequent Concentration Provide a Well-Matched Sample/Buffer Pair for High-Resolution MMS

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Higher-Order Structure Assessment of a Protein Library by Microfluidic Modulation Spectroscopy (MMS)

August 10, 2022

Posters

Higher-Order Structure Assessment of a Protein Library by Microfluidic Modulation Spectroscopy (MMS)

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RedShiftBio at the 2022 Colorado Protein Stability Conference

August 8, 2022

Events

RedShiftBio at the 2022 Colorado Protein Stability Conference

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Protein Dilution and Subsequent Concentration Provide a Well-Matched Sample/Buffer Pair for High-Resolution MMS

July 29, 2022

App Notes

Protein Dilution and Subsequent Concentration Provide a Well-Matched Sample/Buffer Pair for High-Resolution MMS

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Behind the App Note: Measuring Buffer-induced Structural Changes in an Alpha-helix Rich Enzyme

July 20, 2022

Videos

Behind the App Note: Measuring Buffer-induced Structural Changes in an Alpha-helix Rich Enzyme

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Measuring Buffer-Induced Structural Changes in a Beta-sheet Rich Protein using MMS

June 16, 2022

App Notes

Measuring Buffer-Induced Structural Changes in a Beta-sheet Rich Protein using MMS

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Advancing Structural Characterization of Therapeutic Proteins with Microfluidic Modulation Spectroscopy

June 9, 2022

Webinars

Advancing Structural Characterization of Therapeutic Proteins with Microfluidic Modulation Spectroscopy

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High-Pressure, Low-Temperature Induced Unfolding and Aggregation of Monoclonal Antibodies: Role of the Fc and Fab Fragments

June 8, 2022

Publications
The Journal of Physical Chemistry B

High-Pressure, Low-Temperature Induced Unfolding and Aggregation of Monoclonal Antibodies: Role of the Fc and Fab Fragments

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Using MMS to Measure Buffer-Induced Structural Changes in an Alpha-helix Rich Enzyme

May 25, 2022

App Notes

Using MMS to Measure Buffer-Induced Structural Changes in an Alpha-helix Rich Enzyme

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Apollo Launch Webinar

May 24, 2022

Webinars

Apollo Launch Webinar

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RedShiftBio at Formulation & Delivery UK 2022

May 6, 2022

Events

RedShiftBio at Formulation & Delivery UK 2022

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A New Tool for your Biophysical Toolkit, MMS: Automated, IR-Based Protein Structural Analysis for Stability & Formulation Testing

May 6, 2022

Videos

A New Tool for your Biophysical Toolkit, MMS: Automated, IR-Based Protein Structural Analysis for Stability & Formulation Testing

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RedShiftBio at PEGS Boston 2022

May 2, 2022

Events

RedShiftBio at PEGS Boston 2022

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Apollo Product Brochure

May 2, 2022

Brochures

Apollo Product Brochure

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Characterization of Protein Secondary Structure and Aggregation Utilizing Microfluidic Modulation Spectroscopy

May 2, 2022

Videos

Characterization of Protein Secondary Structure and Aggregation Utilizing Microfluidic Modulation Spectroscopy

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HOS Determination of a Highly Pigmented Protein using MMS

April 5, 2022

App Notes

Higher Order Structure Determination of a Highly Pigmented Protein using Microfluidic Modulation Spectroscopy

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RedShiftBio at XVIII Discussions in Structural Molecular Biology and 5th User Meeting of CIISB

March 24, 2022

Events

RedShiftBio at XVIII Discussions in Structural Molecular Biology and 5th User Meeting of CIISB

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RedShiftBio at Biologics UK 2022

March 21, 2022

Events

RedShiftBio at Biologics UK 2022

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Insights into Predicting Aggregation and Particle Formation Behaviour During Early Formulation Screening: The Role of Microfluidic Modulation Spectroscopy

March 21, 2022

Videos

Biologics UK 2022: Insights into Predicting Aggregation and Particle Formation Behaviour During Early Formulation Screening: The Role of Microfluidic Modulation Spectroscopy

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Advanced characterization of Monoclonal Antibodies

March 12, 2022

Publications
Analytical Biochemistry

Advancing Secondary Structure Characterization of Monoclonal Antibodies using Microfluidic Modulation Spectroscopy

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Progress in infrared spectroscopy as an efficient tool for predicting protein secondary structure

February 22, 2022

Publications
International Journal of Biological Macromolecules

Progress in Infrared Spectroscopy as an Efficient Tool for Predicting Protein Secondary Structure

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MMS as a Non-Destructive Structural Characterization Technique

February 18, 2022

App Notes

Microfluidic Modulation Spectroscopy as a Non-Destructive Structural Characterization Technique

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Biologic Drug QA Applications of MMS for Reduced Risk and Better Decision Making

February 15, 2022

Brochures

Using Microfluidic Modulation Spectroscopy for Quality Assurance of Biologic Drugs: Five Applications to Remove Risk and Enable Better, Faster Decision-Making

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MMS Enables Accurate, Sensitive, and Reproducible Secondary Structure Measurements for Biophysical Molecule Characterization

January 18, 2022

Videos

PepTalk 2022 Presentation: AQS³pro and Microfluidic Modulation Spectroscopy - Accurate, Sensitive, and Reproducible Secondary Structure Measurements for Biophysical Molecule Characterization

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RedShiftBio at PepTalk 2022

January 17, 2022

Events

RedShiftBio at PepTalk 2022

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Quality comparability assessment of a SARS-CoV-2-neutralizing antibody across transient, mini-pool-derived and single-clone CHO cells

December 20, 2021

Publications
mAbs

Quality Comparability Assessment of a SARS-CoV-2-neutralizing Antibody across Transient, Mini-pool-derived and Single-clone CHO Cells

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MMS for Detection of Partial Unfolding of Egg White Lysozyme in 2M GuHCl Solution

December 3, 2021

App Notes

Detecting Partial Unfolding of Hen Egg White Lysozyme in 2M Guanidine Hydrochloride Solution using Microfluidic Modulation Spectroscopy (MMS)

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MMS for Predicting Aggregation & Particle Formation Behaviour During Early Formulation

November 4, 2021

Videos

PEGS Europe 2021: Insights into predicting aggregation & particle formation behaviour during early formulation screening: The role of MMS

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AQS³®pro Product Demonstration

November 3, 2021

Videos

AQS³®pro Product Demonstration

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RedShiftBio at PEGS Europe 2021

November 2, 2021

Events

RedShiftBio at PEGS Europe 2021

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AQS³pro Product Brochure

October 30, 2021

Brochures

AQS³pro Product Brochure

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RedShiftBio at Well-Characterized Biologics & Bioassay Digital Event 2021

October 25, 2021

Events

RedShiftBio at Well-Characterized Biologics & Bioassay Digital Event 2021

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Biosimilar Structural Comparison of Sourced Reference Standards

July 29, 2021

App Notes

Biosimilar Structural Comparison of Commercially Sourced Reference Standards by MMS Rapidly Detects Subtle but Critical Differences to Correctly Predict Activity for Use in an ELISA Product

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RedShiftBio at the European Biophysics Conference

July 24, 2021

Events

RedShiftBio at the European Biophysics Conference

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Improving IR Spectroscopy as a Tool for Biopharmaceutical Analysis

July 1, 2021

Articles
Biopharm International

E-book: Improving IR Spectroscopy as a Tool for Biopharmaceutical Analysis

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MMS for Biosimilar Comparison and Accelerated Stability Prediction

June 24, 2021

App Notes

Biosimilar Comparison and Accelerated Stability Predictions Based on <2% Secondary Structure Differences Using Microfluidic Modulation Spectroscopy (MMS)

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Automated Analysis of Protein Higher Order Structure with MMS

May 12, 2021

Webinars
Genetic Engineering News

Automated High-throughput Infrared Spectroscopy for Secondary Structure Analysis of Protein Biopharmaceuticals

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Measuring S. aureus N-Terminus Formylated δ-toxin & Deformylated δ-toxin with MMS

May 7, 2021

Publications
Virulence

Staphylococcus aureus N-terminus formylated δ-toxin tends to form amyloid fibrils, while the deformylated δ-toxin tends to form functional oligomer complexes

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Focusing on Accelerated Formulation Strategies - PharmTech.com

May 4, 2021

Articles
Pharmaceutical Technology

Focusing on Accelerated Formulation Strategies - PharmTech.com

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Long Term Protein Stability Analysis Using MMS

April 29, 2021

Posters

Microfluidic Modulation Spectroscopy of a Biotherapeutic at Low to High Concentrations without Interference from Formulation Excipients

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RedShiftBio at Battle of the Biotechs 2021

April 17, 2021

Events

RedShiftBio at Battle of the Biotechs 2021

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RedShiftBio at HOS 2021

April 12, 2021

Events

RedShiftBio at HOS 2021: 9th International Symposium

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Physicochemical Characterization of Antibody-Drug Conjugates

April 8, 2021

Webinars
LabRoots

Webinar: Physicochemical Characterization of Antibody-Drug Conjugates

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Detection of Pressure-Induced Protein Aggregation with MMS

April 8, 2021

App Notes

Detection of Pressure-Induced Protein Aggregation Using Microfluidic Modulation Spectroscopy (MMS)

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MMS for Analysing Protein Structure Changes Due To Ligand Binding

April 6, 2021

Webinars

Automated Analysis of Protein Secondary Structure Changes Due To Ligand Binding Using Microfluidic Modulation Spectroscopy

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GEN Feature: Secondary Structure Characterization in Bioprocessing

March 22, 2021

Articles
Genetic Engineering News

Making Secondary Structure a Priority in Bioprocessing

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Similarity Testing Conjugate Vaccines

March 4, 2021

Articles
Pharmaceutical Outsourcing Magazine

Developing a New Carrier Protein for Conjugate Vaccines: Analytical Strategies for Similarity Testing and Formulation Development

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Comparison of FTIR Protein Analysis and MMS-Based AQS³pro

December 1, 2020

App Notes

Assessment of Quantitation Linearity for Bovine Serum Albumin Using MMS vs FTIR

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Detecting Protein Conformational Change Due to Ligand Binding

December 1, 2020

App Notes

Detecting Protein Conformational Change Due to Ligand Binding and Stabilization Using MMS

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Protein Analysis Tools: Higher Order Structure of Insulin

December 1, 2020

App Notes

Secondary Structure Analysis: Using Microfluidic Modulation Spectroscopy to Determine the Structural Effect of pH on the Peptide Hormone Insulin

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Clark University: Structural Characterization of Insulin-Degrading Enzyme

November 6, 2020

Posters

Structural Characterization of the Insulin-Degrading Enzyme by Microfluidic Modulation Spectroscopy

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Clark University: Early Amyloid Formation by Lysozyme Detected by MMS

November 6, 2020

Posters

Early Events in Amyloid Formation by Lysozyme Detected by Microfluidic Modulation Spectroscopy

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Enhanced Protein Structural Characterization using MMS

November 6, 2020

Posters

Enhanced Protein Structural Characterization using Microfluidic Modulation Spectroscopy

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Amgen Poster: MMS for Secondary Structure Analysis of Biopharmaceuticals

November 6, 2020

Posters

Microfluidic Modulation Spectroscopy (MMS) - a novel automated infrared (IR) spectroscopic tool for secondary structure analysis of biopharmaceuticals with high sensitivity and repeatability

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Pfizer Demonstrates Repeatability, Concentration Linearity and HOS Analysis of IgG1 with MMS

November 6, 2020

Posters

Repeatability, Concentration Linearity, and High Order Structure Analysis of an IgG1 Sample by Microfluidic Modulation Spectroscopy (MMS)

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Thermal Denaturation Analysis of Bovine Serum Albumin by MMS

November 6, 2020

Posters

Thermal Denaturation Analysis of Bovine Serum Albumin by Microfluidic Modulation Spectroscopy

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Pfizer Poster: High Order Structure Analysis of IgG1

November 6, 2020

Posters

Comparability, Similarity, Linearity and High Order Structure Analysis of an IgG1 Sample by Microfluidic Modulation Spectroscopy

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HOS Study for IgG Samples Spiked with Different Amount of BSA by MMS

November 6, 2020

Posters

HOS Study for IgG Samples Spiked with Different Amount of BSA by Microfluidic Modulation Spectroscopy

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Measuring Pressure-Perturbation of Protein Secondary Structure with Microfluidic Modulation Spectroscopy

November 6, 2020

Publications
Biophysical Journal

Pressure-perturbation of protein secondary structure coupled with Microfluidic Modulation Spectroscopy – a powerful platform for biopharmaceutical formulations development

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MMS of a Biotherapeutic at Low to High Concentrations without Excipient Interference

November 6, 2020

Posters

Microfluidic Modulation Spectroscopy of a Biotherapeutic at Low to High Concentrations without Interference from Formulation Excipients

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MMS for Protein Characterization Case Study with EcoCRM, CRM197 Carrier Protein

November 6, 2020

Posters

Microfluidic Modulation Spectroscopy for Protein Characterization A Case Study with EcoCRM, CRM197 Carrier Protein

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Differentiation of <2% changes in HOS using Microfluidic Modulation Spectroscopy (MMS)

November 6, 2020

Posters

Confident Differentiation of <2% changes in Secondary Structure to Compare Batch-to-Batch Activity using Microfluidic Modulation Spectroscopy (MMS)

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Secondary Structure Determination in Biologics Using MMS

October 1, 2020

App Notes

Secondary Structure Determination using Microfluidic Modulation Spectroscopy in the Presence of DMSO

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Characterizing Monoclonal Antibody Structure with AQS³pro

October 1, 2020

App Notes

Secondary Structure Analysis of NIST Monoclonal Antibody Reference Material 8671 by Microfluidic Modulation Spectroscopy

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The Analytical Scientist: HOS analysis in the biopharmaceutical industry

September 3, 2020

Articles
Analytical Scientist

Fast and Furious HOS Analysis?

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Higher Order Structure of Proteins in Biopharmaceutical Development

August 6, 2020

Webinars

Higher Order Structure Biocompatibility by MMS of Active and Inactive Biosimilars

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