Aurora TX

Aurora TX

Aurora TX

The One-Drop Protein & RNA Characterization Solution

Precise, Automated, and Ultra-Sensitive Biomolecule Characterization

Automated Sample Handling

Fully Automated Sample Handling System

Reduces hands-on time and human error

High power quantum cascade laser

High Power Quantum Cascade Laser

Provides 30x sensativity to detect small changes in structure over wide concentration ranges.

Microfluidic Modulation Spectroscopy (MMS)

High Precision Microfluidic Flow Cell

Enables extreme reproducibilityand allows use of complex buffers

Touchscreen and Ease of Use

Simple Operation, Integrated touchscreen, and Advanced Analytics

Ease of use with minimal training and high-quality data

Thermal Ramping MMS

Thermal Ramping

Stability

Aurora TX

The AuroraTX Platform: Powered by MMS

Superior Sensativity

30x increase vs FTIR

Unmatched Speed

Fast analysis with minimal hands-on time

Versatile Applications

Proteins, peptides, RNA in one platform

Reliable Results

>98% system repeatability

MMS Diagram
Aurora TX

Microfluidic Modulation Spectroscopy (MMS)

Unique microfluidics alternates sample and buffer in flow cell

  • Differential Absorbance (DiffAU) recorded in simple and very complex backgrounds with equal ease.
  • >98% system repeatability at 2mg/ml, with perfect subtraction.
  • >99.9% possible at increased conc.!
  • In situ measurements in H20 and a very wide range of buffers, excipients and organic solvents.
  • Learn more about Microfluidic Modulation Spectroscopy
Microfluidic Modulation Spectroscopy (MMS)
Microfluidic Modulation Spectroscopy (MMS)
Aurora TX

Why is Secondary Structure Important?

  • Structure and activity are directly related
  • Misfolding may reduce function and/or lead to the formation of undesired species
  • MMS very sensitively measures protein structure in situ, and reproducibly detects even very small differences between samples, outside the capabilities of traditional technologies
  • This fundamental IR-based technique has many applications, including:
    • Quality Control for batch-to-batch reproducibility
    • Manufacturability
    • Identification for Biosimilarity
    • Stress Testing
    • Direct Comparisons for Formulation Development, without the need for any additional user setup
    • Aggregation
      • Parallel versus anti-parallel beta-sheet formation
    • Conformational change on Ligand Binding
    • Accelerated Stability
    • In-Process Monitoring
    • Structural Melts
    • Many more!

If you’d like more information or to schedule a technical discussion with our scientists, contact Redshift today.

Secondary Structure

Request a Demo Today! 

RedShiftBio AQS3 Product Detail