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Behind the App Note: MMS as a Non-Destructive Structural CharacterizationTechnique: A Case Study Using BSA

January 20, 2023

RedShiftBio's Dr. Richard Huang explains how Microfluidic Modulation Spectroscopy was used to analyze a complex sample, bovine serum albumin (BSA), in phosphate-buffered saline (PBS), to validate the non-destructive nature of MMS.

Results showed that the structures of the BSA samples were almost identical before and after analysis with greater than 99% similarity. Furthermore, the study demonstrated that by re-concentrating the post-process diluted sample back to the original volume, the recovery rate is approximately 95% with greater than 99% similarity compared to the original sample.

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