May 15-19, 2023
The world’s largest gathering of protein engineering and biotherapeutics experts is back in Boston and RedShiftBio will be there! Visit us at Booth 1214!
PEGS Boston Summit is the leading biologics event with comprehensive programming covering all aspects of biologic drug development with in-depth presentations on protein and antibody engineering, immunotherapy, oncology, expression, analytics, immunogenicity, and more.
Harness the power of in-person events, form genuine connections, create valuable relationships with peers, and become part of the PEGS community.
RedShiftBio will be presenting in the Characterization for Novel Biotherapeutics on Friday, May 19th at 10:00am.
Structural Characterization and Temperature and Pressure Stress Comparison on Ovalbumin using MMS
Temperature-stress and melt curves are common stress conditions tested forgauging protein stability, however, melt curves can appear very different, yet produce the same Tm. Microfluidic Modulation Spectroscopy can help deconvolve the resulting structural changes that lead to protein unfolding. A comparison of temperature and pressure stress was applied to ovalbumin, showing that each stress unfolds ovalbumin differently. Understanding structural details aids in better overall drug design.
Structure, Stability, Similarity, and Stress Characterization of Trastuzumab and Two Biosimilar Drugs Using Microfluidic Modulation Spectroscopy (MMS)