Discover cutting-edge solutions in protein analysis and RNA characterization with RedShiftBio, proud sponsor of PepTalk 2024. Elevate your research with our innovative MMS technology designed to enhance precision and efficiency in biomolecule structural analysis. Visit us at Booth 713 to learn more about our contributions to advancing scientific understanding!
Track: Characterization of Biotherapeutics
Title: Microfluidic Modulation Spectroscopy (MMS) for Monitoring Protein Structure During Re-Folding and Thermal Stress
Protein stability is a critical quality attribute for a new biologic drug. To investigate stability through folding and unfolding, we stressed multiple proteins both thermally and with pressure and measured the changes in the protein structure and melting point (Tm) using MMS. We will also discuss a novel method for re-solubilizing and re-folding proteins using urea and pressure resulting in natively folded proteins whose structure matches that of the original unstressed protein.
Date and Time: Wednesday, January 17 at 03:05 PM - 03:20 PM
Presented by David Sloan, PhD
January 16-17, 2024
A30: A Structural Characterization of a Monoclonal Antibody Therapeutic as Formulated and Under Multiple Conjugation Paradigm
Presented by Maria Ma, PhD
Missed our Poster Session? Reach out to us for a downloadable copy!